GitHub repo leaderboard by stars, growth rate and activity.

• K-Dense-AI

  #1K-Dense-AI/scientific-agent-skills

  Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.

  Python44,138 starslast pushed 4 days ago
• aipoch

  #2aipoch/open-science

  AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.

  TypeScript4,002 starslast pushed 22 hours ago
• synthetic-sciences

  #3synthetic-sciences/openscience

  The open-source AI workbench for scientific research

  TypeScript3,545 starslast pushed 24 hours ago
• K-Dense-AI

  #4K-Dense-AI/k-dense-byok

  An AI co-scientist running on your desktop. Claude Science but better.

  TypeScript1,193 starslast pushed 2 days ago
• xuzhougeng

  #5xuzhougeng/wisp-science

  Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

  Rust1,118 starslast pushed 23 hours ago
• beita6969

  #6beita6969/ScienceClaw

  🔬🦞 A self-evolving AI research colleague for scientists. 285 skills, zero hallucination, persistent memory.

  TypeScript898 starslast pushed 3 months ago

#	Repo	Language	Stars	30-day trend	Last updated
1	K-Dense-AI K-Dense-AI/scientific-agent-skills Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.	Python	44,138		last pushed 4 days ago
2	aipoch aipoch/open-science AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.	TypeScript	4,002		last pushed 22 hours ago
3	synthetic-sciences synthetic-sciences/openscience The open-source AI workbench for scientific research	TypeScript	3,545		last pushed 24 hours ago
4	K-Dense-AI K-Dense-AI/k-dense-byok An AI co-scientist running on your desktop. Claude Science but better.	TypeScript	1,193		last pushed 2 days ago
5	xuzhougeng xuzhougeng/wisp-science Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.	Rust	1,118		last pushed 23 hours ago
6	beita6969 beita6969/ScienceClaw 🔬🦞 A self-evolving AI research colleague for scientists. 285 skills, zero hallucination, persistent memory.	TypeScript	898		last pushed 3 months ago

All · 11,474