GitHub repo leaderboard by stars, growth rate and activity.

• aipoch

  #1aipoch/open-science

  AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.

  TypeScript4,042 starslast pushed 56 minutes ago
• mims-harvard

  #2mims-harvard/ToolUniverse

  Democratizing AI scientists with ToolUniverse

  Python1,680 starslast pushed 2 days ago
• ai4s-research

  #3ai4s-research/open-science

  Open Science Desktop — local-first, model-agnostic AI research workbench for macOS, Windows & Linux. Open-source Claude Science desktop alternative built on Tauri + MCP + agent skills.

  TypeScript1,628 starslast pushed 1 hour ago
• xuzhougeng

  #4xuzhougeng/wisp-science

  Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

  Rust1,125 starslast pushed 1 hour ago

#	Repo	Language	Stars	30-day trend	Last updated
1	aipoch aipoch/open-science AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench for macOS, Windows, and Linux, with scientific agents, Python/R notebooks, data connectors, and reproducible provenance.	TypeScript	4,042		last pushed 56 minutes ago
2	mims-harvard mims-harvard/ToolUniverse Democratizing AI scientists with ToolUniverse	Python	1,680		last pushed 2 days ago
3	ai4s-research ai4s-research/open-science Open Science Desktop — local-first, model-agnostic AI research workbench for macOS, Windows & Linux. Open-source Claude Science desktop alternative built on Tauri + MCP + agent skills.	TypeScript	1,628		last pushed 1 hour ago
4	xuzhougeng xuzhougeng/wisp-science Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.	Rust	1,125		last pushed 1 hour ago

All · 11,658