GitHub repo leaderboard by stars, growth rate and activity.
Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.
Burn is a next generation tensor library and Deep Learning Framework that doesn't compromise on flexibility, efficiency and portability.
XGo is a programming language that reads like plain English. But it's also incredibly powerful — it lets you leverage assets from C/C++, Go, Python, and JavaScript/TypeScript, creating a unified software engineering ecosystem. Our vision is to enable everyone to become a builder of the world.
The open-source AI workbench for scientific research
Open-source software for volunteer computing and grid computing.
An AI co-scientist running on your desktop. Claude Science but better.
Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.
Evidence-constrained commercialization assessment with deterministic retrieval, six LLM stages, auditable scoring and checkpoint recovery.
| # | Repo | Language | Stars | 30-day trend | Last updated |
|---|---|---|---|---|---|
| 1 | Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard. | Python | 44,138 | last pushed 4 days ago | |
| 2 | Burn is a next generation tensor library and Deep Learning Framework that doesn't compromise on flexibility, efficiency and portability. | Rust | 15,889 | last pushed Yesterday | |
| 3 | XGo is a programming language that reads like plain English. But it's also incredibly powerful — it lets you leverage assets from C/C++, Go, Python, and JavaScript/TypeScript, creating a unified software engineering ecosystem. Our vision is to enable everyone to become a builder of the world. | Go | 9,458 | last pushed Yesterday | |
| 4 | The open-source AI workbench for scientific research | TypeScript | 3,545 | last pushed Yesterday | |
| 5 | Open-source software for volunteer computing and grid computing. | C++ | 2,463 | last pushed 24 hours ago | |
| 6 | An AI co-scientist running on your desktop. Claude Science but better. | TypeScript | 1,193 | last pushed 2 days ago | |
| 7 | Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models. | Rust | 1,118 | last pushed Yesterday | |
| 8 | Evidence-constrained commercialization assessment with deterministic retrieval, six LLM stages, auditable scoring and checkpoint recovery. | Python | 782 | last pushed 3 days ago | |
| 9 | The Go/XGo Interpreter | Go | 142 | last pushed 1 week ago |
All · 11,474